The rationale is that two smaller doses produce a more even medication level throughout the week, avoiding the peak-and-trough pattern that creates intense digestive effects early in the week and diminishing effects late in the week
As both GLP-1 analogues and DPP-4 inhibitors are increasingly used in the management of T2DM (more often in combination therapy with metformin) [17], one important question that may arise is which one of the two drug classes is more favorable as a second-line treatment of T2DM [18], [19]
Expert insight from our panelists: Morgan Lee, PhD, MPH, CPH Vice President, Research & Marketing Scott Halperin, PharmD Vice President, Employer Pharmacy Benefit Consulting Steve Altenburger, PharmD Senior Pharmacy Benefit Consultant
The key point is choosing a time you can stick with every day
together, they can improve body composition, cardiovascular health, and emotional well-being