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The glutathione S-transferase genes code for enzymes involved in the removal of a variety of carcinogens and environmental toxins.[ref] These phase II detoxification enzymes combine the metabolites from phase I with molecules that make them less toxic and more easily excreted

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Molecular mechanism of the ichthyosis pathology of ChanarinDorfman syndrome: stimulation of PNPLA1-catalyzed - O -acylceramide production by ABHD5