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Purchases through TrumpRx will not go through insurance, but will instead be out-of-pocket purchases, so price advantages and disadvantages will vary depending on insurance coverage (Lupkin, 2025) Pfizer, Eli Lily, AstraZeneca, and Novo Nordisk have already negotiated prices for medications to be made available via the TrumpRx website, and the Trump administration has stated it will continue to expand negotiations with manufacturers (The United States Government, 2025b, 2025c)
While not directly addressing the legitimacy of patient-specific compounding of GLP-1 products, FDA has sent a cautionary sign to 503A pharmacies operating in this space
Thats if they spot the products in store all the retailers appear to have avoided GLP-1 friendly claims at point of sale except Morrisons, which has included the phrase on pack
2.5 Bariatric surgery Bariatric surgery is an option in patients unresponsive to lifestyle changes and pharmacotherapy
The Journal of Pharmacology and Experimental Therapeutics has retracted this article. In September 2024, Athira Pharmas LIFT-AD trial of fosgonimetona clinical derivative of Dihexafailed to meet primary and secondary endpoints in 312 mild-to-moderate Alzheimers patients
