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The MariTide Phase 2 data presented in November 2024 were highly significant: MariTide demonstrated robust weight loss at 52 weeks with no plateau meaning continued weight loss trajectory at the end of the study period, unlike semaglutide and tirzepatide which show plateau effects and significant improvements in cardiometabolic parameters
Ct value was first normalized to ACTB for each sample, then to VEH for each cell line, and expressed as mean SD with P values were determined by unpaired 2-tailed t test with Welch correction for unequal variances
M., Lillig, C
Making these decisions requires an executive who can hold the commercial tension between protecting near-term revenue and making resource allocation decisions that the data says are necessary, which is not the same skill as growing a category in a tailwind
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