Once activated, ERK1/2 is transferred to the nucleus, where it phosphorylates transcription factors such as c-Myc and c-Fos, leading to the expression of genes responsible for cellular regulations such as cell proliferation, differentiation, and migration
We also sought to explore the nature of cell death involved and examine whether RPE cells experience SIPS following GSH depletion
FIGURE 1 DPP-4 is member of a family of proteases which also includes dipeptidyl-peptidase-8 (DPP-8), dipeptidylpeptidase-9 (DPP-9) and fibroblast activation protein (FAP) (Ajami et al., 2004)
Effect of once-weekly subcutaneous semaglutide on arterial inflammation in people with type 2 diabetes and cardiovascular disease using PET-MRI: primary results of a randomized, double-blind, placebo-controlled trial
e-value threshold is 0.01