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Gallbladder Problems: Sudden, severe upper abdominal pain, nausea, vomiting, fever, or yellowing of the skin or eyes

Site Irritation Because DES is injected intramuscularly into the trained muscle, injection site soreness or redness can occurespecially with repeated use in the same muscle group

If generalized skin dryness or sensitivity develops during treatment, optimize skincare practices with gentle, fragrance-free cleansers and moisturizers

Obesity in Adults: Drug Therapy. Edited by F Xavier Pi-Sunyer and Sara Swenson, UpToDate, Wolters Kluwer, 21 Dec

Limitation: because the signal is brief, sermorelin generally requires daily injection, typically at bedtime to coincide with your bodys largest natural overnight GH surge