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Inositol shows the strongest evidence in PCOS populations, with modest BMI reduction in meta-analyses
Requirements of vitamin B12 in excess of normal (due to pregnancy, thyrotoxicosis, hemolytic anemia, hemorrhage, malignancy, hepatic and renal disease) can usually be met with oral supplementation
These injections, sometimes called a B12 shot, are administered intramuscularly, ensuring immediate absorption and utilization by the body
The frequency of these injections can vary from daily to monthly, depending on how severe the deficiency is and how well the patient responds
Semaglutide improves it through glucose-dependent insulin secretion
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