If left untreated, it can cause irreversible damage to the brain, spinal cord, heart, and other organs
Some practitioners theorize that local administration to abdominal fat may enhance regional lipolytic effects, though this has not been conclusively proven
Excipient studies on lyophilized rhGH show that sugar and polyol stabilizers (mannitol, sucrose, trehalose) protect the protein's secondary structure and limit aggregation in the dry state by satisfying water-binding sites and stabilizing the amorphous matrix around the protein (Costantino et al., 1998)
There may well be some patients who feel they do fine on 4 injections per year (or dont want to say otherwise) however those patients dont write to me or join support groups
One distinctive feature of these compounds is a 4.5% cobalt content, hence the name cobalamin" (cobalt + vitamin)