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Patients should be aware that research in this area is ongoing, and long-term safety and efficacy data may be limited for certain therapies

Chemotherapy-induced peripheral neuropathy Four randomized controlled trials (RCTs) have evaluated the use of acetyl-L-carnitine (LC) for the prevention of chemotherapy-induced peripheral neuropathy (CIPN)

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Specifically, it significantly increases the production of Type I and III collagen, as well as elastin, in fibroblasts