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Bath application of GLP-1 induces a depolarization in most hippocampal neurons and a hyperpolarization in a few neurons ( in vitro electrophysiological recordings further demonstrated that exendin-4 elicits an early fast excitatory response dose-dependently (Hsu et al., 2015, 2018)
In the Phase III innovaTV 301 study, which enrolled more than 500 patients, Tivdak significantly boosted survival versus chemotherapy
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The regulatory nod is the first new frontline treatment for patients whose cancer is mismatch repair deficient (dMMR) or microsatellite instability-high (MSI-H) in decades, according to GSK
This dual-action mechanism supports more significant weight loss compared to other treatments, making it an excellent option for those struggling to manage their weight
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