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DNA Repair: NAD+ is a substrate for enzymes such as sirtuins and PARPs, which repair damaged DNA and maintain genomic stability
Two severe adverse events were reported: viral meningitis (in cagrilintide 1.2 mg + semaglutide 2.4 mg) and an increase in serum creatinine (in placebo + semaglutide 2.4 mg), but both events were deemed unrelated to study treatment by the study investigator
Some users experience mild nasal irritation, particularly with initial use
The GLP-1 receptor agonist class began with compounds like liraglutide and exenatide, targeting only the GLP-1R
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