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For patients with Long COVID and ME/CFS, restoring the intracellular ratio of reduced to oxidized glutathione is paramount for breaking the mitochondrial doom loop
Where it can be found
Brenda: The Comprehensive Enzyme Information System
Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease
Wilkins et al., 2012), mainly in kidney and liver, and tricarboxylate carrier (TTC, SLC25A1) in brain mitochondria and astrocytes (Wadey et al., 2009)
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