Instead of just raising blood sugar, it: Increases energy expenditure (your body burns more calories at rest) Enhances fat oxidation (your body preferentially burns fat for fuel) Improves liver fat metabolism (reduces fatty liver disease) Boosts metabolic rate without causing dangerous blood sugar spikes The GLP-1 and GIP components keep blood sugar in check while the glucagon component supercharges fat burning
10.1161/CIRCULATIONAHA.119.041886 81 SongX.JiaH.JiangY.WangL.ZhangY.MuY.et al (2015)
Cushing syndrome , whether from excess cortisol production or chronic steroid use, causes characteristic central weight gain
Getting enough protein is vital to minimizing muscle loss on GLP-1s Fiber intake is important because GLP-1s slow down digestion
Indeed, in the group of 1,341 patients that were classified as having HFrEF, the event rate for the composite of HHF or cardiovascular death recorded in the placebo arm was much lower (only 4%) compared to what was observed in other HFrEF CVOTs, including the EMPEROR-Reduced (21.0%) [57] and DAPA-HF (15.6%) [58] trials