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Apply a small amount on a discreet skin area and wait 24-48 hours to observe any adverse reactions
This is the precise point where partial knowledge becomes costly in both time and outcomes
Stagger them by at least 6-8 hours
In rare, carefully controlled situations when a patient is facing otherwise life-threatening inflammatory disease the clinician and patient may decide the risk is worth it
Acknowledgements The authors acknowledge the logistic support and laboratory facilities of the Department of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet, Bangladesh
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