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Short-term effects (first 12 weeks) Injection-site irritation : redness, itching, or swelling Headaches or nausea : usually mild and temporary Fatigue or drowsiness : some people feel extra tired at the start Water retention or bloating : often resolves as your body adjusts Occasional but less common effects Joint stiffness or aches Tingling or numbness (paresthesia, often in the hands or feet) Increased appetite These usually fade as your body adapts, but if they linger, its worth checking in with your provider
It's important to note that in most human studies, GLP-1 was measured as a secondary or exploratory endpoint rather than the primary outcome, limiting the strength of conclusions that can be drawn
People who participated in these trials avoided relapsing into smoking at 24 weeks and 52 weeks
Older people are susceptible to deficiency because they do not produce enough hydrochloric acid in their stomachs to absorb the Vitamin B12 in the food they eat
"You must stop breastfeeding to take semaglutide" Reality: The research into the risks of taking semaglutide while breastfeeding is ongoing, but a very small initial study shows encouraging findings that none of the medication transfers to the breastfeeding baby
