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For orthopaedic use, mesenchymal stromal cells (MSCs) are the cell type of interest as they have the capacity to differentiate into tendon, ligament, muscle, cartilage and bone

What we do not know Several questions remain unanswered: Does prolonged amylin receptor agonism produce any adaptive changes in receptor expression or sensitivity that could alter efficacy or safety over years

Human trials show mild improvement in knee osteoarthritis symptoms

Managing Side Effects Dose Titration: Gradually increasing the dose may help minimize gastrointestinal discomfort