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NMR spectroscopy NMR experiments were performed using a Bruker 900 MHz NMR spectrometer equipped with a cryogenic probe (KBSI, Ochang) and a Bruker 600 MHz NMR spectrometer equipped with a cryogenic probe (GIST, Gwangju)

Patients with pre-existing hypertension or genetic variants affecting vascular reactivity may experience greater sensitivity, making baseline monitoring and personalized dose titration essential for safety

Most patients describe the nausea as mild to moderate, and many find it manageable with dietary adjustments like eating smaller, blander meals

Additional concerning features include the development of a widespread rash, blistering, skin discoloration, or itching severe enough to disrupt sleep or daily activities

The better your medication quality, the more accurately the plotter reflects your actual pharmacokinetic experience