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Recently, it was shown that cysteine uptake via excitatory amino acid carrier 1 suppresses ischemia-induced neuronal death through promotion of hippocampal GSH synthesis in ischemic animal models (162)
GHK is a small peptide (a short chain of amino acids) that binds copper ions
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The most limiting material for synthesizing GSH is cysteine, and inhibiting its uptake through the SystemX c could induce ferroptosis in vitro (Doll and Conrad, 2017
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