For the primary composite outcome and secondary hierarchical outcomes, the threshold for two-sided statistical significance was set to 0.0322 (one-sided level 0.00161) using Lan-DeMets alpha spending function, which allows to adjust significance levels as data were reviewed for the interim analysis, reducing the chance of false positive results
Article: Why Your Skin Still Looks Dull (Even After Expensive Skincare) Why Your Skin Still Looks Dull (Even After Expensive Skincare) Youre doing everything right serums, moisturizers, sunscreen yet your skin still looks dull
The MASH trials main goals are to improve liver fibrosis and resolve steatohepatitis without worsening either condition in people with MASH
Gradually increase your fiber intake through fruits, vegetables, and whole grains, aiming for 25-30 grams daily
"Remember, there is a delay between eating and ones perception of satiety," Osborn said