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Trial protocols, food advice, and exercise guidance also differed across the studies
Specialized liquid chromatography-tandem mass spectrometry (LC-MS/MS) assays can detect tirzepatide in plasma and urine for research purposes, but this testing is not part of any routine panel
Despite these underwhelming results, Novo considered the results to be promising and still expects to submit the drug for regulatory approval towards the end of 2025
contraindicated in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2
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