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This figure is directly comparable to the performance of tirzepatide (Mounjaro) in the SURMOUNT-1 trial, which showed approximately 20.9% weight loss at 72 weeks, and exceeds the approximately 14.9% achieved by semaglutide alone in STEP 1

Rather than calculating a target mass per administration, topical research formulates the peptide at a target concentration in a carrier base, then applies a consistent volume of the formulation to the research area

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