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It is important to mention that the research team took their experimental procedures a step further in order to define the relationship between Dihexa and the PI3K/AKT signaling pathway, wortmannin, a PI3K inhibitor, was administered to the mice intragastrically to detect the number of neuronal cells and inflammatory factors present

Depending on the individual, different results may be achieved

By bypassing the harsh stomach environment, more intact peptide molecules theoretically survive to reach absorptive tissues

Brain Res Bull

In fact, using the lowest effective dose is the approach most researchers recommend