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Elevated IL-1 levels in UC patients weaken the intestinal barrier, permitting immune cell influx into the lamina propria and aggravating epithelial injury, thereby accelerating disease initiation (85)

Rapid clearance means that even a significant excess dose is substantially eliminated within 3 to 4 hours, limiting the window of any pharmacologic effect

The human body contains approximately 2035 g of L-carnitine, and small amounts can be synthesised internally if the necessary building blocks and cofactors such as vitamin C, B3, B6, and iron are available

Cruciferous vegetables: Broccoli, cauliflower, kale, and Brussels sprouts are rich in sulfur compounds that support glutathione production

doi: 10.1016/j.jep.2024.118895 200 FakhriSMoradiSZDeLibertoLKBishayeeA