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But the primary concern is the risk of ochronosis, a rare but challenging condition where long-term overuse paradoxically causes darkening of the skin, says Francesa Lewis, MD, a board-certified dermatologist in Delray Beach, Florida
J Obstet Gynaecol
Salvio G, Cutini M, Ciarloni A, Giovannini L, Perrone M, Balercia G
Journal of Clinical Epidemiology, 47 (9), 10211026
While all of these compounds stimulate natural growth hormone release, they differ in their side effects, duration of action, and interaction with other hormones like ghrelin , cortisol , and prolactin
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