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As with any GLP1/GIP medication, it is important for healthcare providers to monitor patients taking GLP1/GIP medication to ensure it is being used safely and effectively
The second class is inhibitors of the GLP-1 degrading enzyme, dipeptidyl pepitidase IV (Sitagliptin and related drugs) which can be given orally and increase the plasma level of GLP-1 and other peptides degraded by DPP-4
Key Characteristics: Mechanism: Binds to ghrelin receptors to stimulate growth hormone release from the pituitary gland Selective Action: Triggers GH release without significantly increasing cortisol or prolactin , making it more targeted and safer for long-term use compared to older secretagogues Half-life: Approximately 2 hours , so it is cleared quickly from the body
Sustained attention may still require effort, structure, and the right environment
Hashimoto, N
