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For these reasons, we measured phosphorylation of two phosphorylation sites in ERK1/2 in HepG2 cells and found that CoQ 10 H 2 inhibited phosphorylation of ERK1/2 in cells, while total ERK1/2 content was not changed (Fig

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The STEP UP trial, a Phase 3b study published in The Lancet Diabetes & Endocrinology in 2025, evaluated a 7.2 mg weekly injection dose in over 1,400 adults with obesity (BMI of 30 or higher) and without diabetes