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The body's adaptive response to caloric restriction may prioritise essential physiological functions over non-essential processes like hair growth

Think of that peptide chain like a delicate, intricate key

It is referring to the potential energy contained in the chemical bonds of food that is captured throughout the course of metabolism

However, peripheral melanocortin receptors in adipose tissue, muscle, and liver also contribute to metabolic regulation, suggesting multi-tissue coordinated responses to melanocortin signaling