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Zanza C et al (2022) Cytokine Storm in COVID-19: Immunopathogenesis and Therapy
It produces more modest weight loss than GLP-1 agonists (typically 35% body weight)
However, anaesthetists must take into account the theoretical increased risk of aspiration in patients taking GLP-1 agonists, as presented by the aforementioned case reports
69, suppl
So far, three major problems have kept GLP-1 drugs injectable rather than oral: enzymatic degradation, poor bioavailability, and the sheer cost of manufacturing
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