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However, its still emerging in the research field, with limited human studies to back its efficacy
Ishikawa, S
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[69] demonstrated that the knockdown of FoxO3a enhanced cellular senescence in human dermal fibroblasts indicating that FoxO3a might maintain cellular homeostasis, probably by enhancing autophagy
Regulatory bodies approved GLP-1 receptor agonists are TRULICITY (dulaglutide), BYETTA/BYDUREON (exenatide), VICTOZA (liraglutide), OZEMPIC/WEGOVY/RYBELSUS, (Semaglutide), MOUNJARO/ZEPBOUND (tirzepatide) and others
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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