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L.RupprechtL
10.3389/fnmol.2022.927334 92 LiuJ
Scientifically, miraculous outcomes are now very much possible
While all GLP-1 receptor agonists effectively lower hemoglobin A1c and promote weight loss, there are meaningful differences in their magnitude of effect, titration schedules, and adverse effect profiles that influence clinical decision-making
These results indicate that the increased amount of non-12-OH FXR-antagonistic BAs consequent to the decrease in CYP8B1 expression after T3 treatment potentiates GLP-1 production by deactivating the intestinal FXR, thereby improving glucose homeostasis via the augmentation of insulin secretion
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