Surprisingly, two of them are practices often undertaken to improve health: a vegetarian diet and weight-loss surgery
J Mol Med (Berlin Germany) (2020) 98(3):40923
For instance, when intra-portal insulin levels are increased [e.g., obesity, Cushings syndrome or due to treatment with glucocorticoids and glucagon-like peptide-1 receptor agonists (GLP-1RA)] or decreased (e.g., anorexia nervosa and T1D) in disease states, these secondary changes (secondary association) alters hepatic GH sensitivity resulting in discordant GH and IGF-I levels (high GH/low IGF-I levels and low GH/high IGF-I levels, respectively)
However, evidence for use in humans is limited and experimental
In pattern hair loss, DHT drives dermal papilla cells to secrete DKK1 (Dickkopf-1), a protein that shuts down Wnt signaling