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This results in activated T cells & B cells that produce an anti-citrulline inflammatory response that affects the joints, resulting in swelling and degradation of both cartilage and bone (Schur & Firestein, 2012) as illustrated in Figures 3, 4 & 5

Lifestyle steps such as a paced return to activity, graded exercise, good sleep, and a balanced diet support healing

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However, long-term use does not mean the same dose forever

Patients can benefit from medically assisted weight loss without the need for invasive surgeries or harsh stimulants