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doi: 10.3389/fimmu.2018.02499 30 CaoJLiaoSZengFLiaoQLuoGZhouY

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Clinical trials demonstrate that maximal therapeutic effects generally require several months of treatment at the target maintenance dose, which is typically reached through a gradual dose escalation process

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Nevertheless, it is always advisable to consult the doctor before commencing IV treatment

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For researchers, this highlights the need to stratify outcomes not only by dose but also by starting weight, ensuring that comparisons across arms are meaningful

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Phase 3 trial results show competitive weight loss numbers

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