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If youre experiencing low energy, difficulty building or maintaining muscle, increased body fat, poor sleep, or slower recovery, peptide therapy with Semorelin and Ipamorelin may help restore balance

Wegovy injections are taken once a week, and retatrutide is also being studied as a once-weekly injection

Key takeaways Semaglutide fatigue is real and happens because the medication lowers blood sugar and reduces food intake, leaving you with less available energy

The most common AEs reported for both cohorts included headache responsive to analgesia, tiredness, and dyspnea (Table 1)

The drugs often come with side effects, commonly including nausea, constipation and diarrhoea.