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Severe low testosterone symptoms may necessitate starting with TRT, while significant weight loss goals might prioritize a GLP-1 like semaglutide. One of the biggest concerns when starting two medications at the same time is that if a side effect occurs, it can be difficult to know which one caused it, says Staheli
Eguchi N, Vaziri ND, Dafoe DC, Ichii H
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Two studies investigated animal models of comorbid depression and epilepsy 159,161 : one showed that exendin-4 led to an increase in frequency of absence seizures as well as depressogenic and anxiogenic responses 159 , while the other saw a decrease of depression-like behavior for liraglutide irrespective of concurrent use of the antiepileptic levetiracetam 161
doi:10.3390/nu13061913
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