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To confirm Andexxas clinical benefit AstraZeneca used data from the Phase IV ANNEXA-I study, which found that the drug could induce significantly better hemostasis in patients with acute intracranial bleeding than usual care

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One analysis article suggests they strengthen the blood-brain barrier, lower oxidative stress, and enhance neuron survival

No se recomienda su uso durante el embarazo o perodo de lactancia

And it does not eliminate the need for the one thing that protects patients more than any regulatory change: a physician who understands their biology, orders the appropriate labs, determines clinical indication, and monitors their response