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In addition, exendin-4 protects against cardiac ischemia/reperfusion injury in rats by enhancing antioxidant levels and inhibiting c-Jun NH2-terminal kinase (JNK)/p 66 Shc/NADPH oxidase axis [13]
BV inhibits tyrosinase-related proteins, resulting in antimelanogenic action (Han et al., 2015)
For the quantification of sulfur metabolites in serum, the metabolites in 20 uL of serum were extracted and derivatized by NEM in 80 L of ice-cold extraction solvent (80% MeOH: 20% H2O containing 25 mM NEM and 10 mM ammonium formate, pH = 7.0) which includes stable isotope labeled internal standards (1 M [ 13 C 3 , 15 N]-cysteine-NEM, 0.1 M [ 13 C 2 , 15 N]-GSH-NEM, 2 M [D 4 ]-Cystine, 4.6 M [ 13 C 5 , 15 N 2 ]-GSSG, 5 M [D 4 ]-Hypotaurine, and 40 M [ 13 C 2 ]-Taurine followed by incubation at 4 C for 30 min
The compound stands apart from other growth hormone releasers due to its selectivity
