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We created a comprehensive cellular atlas of inflammatory responses and their resolution across vehicle, LPS, and semaglutide treatment using single-nucleus RNA sequencing (snRNA-seq)
Start Low, Titrate Slowly The standard titration protocol starts at 1mg/week and escalates gradually
The study looked at those who quit within less than three months, and those who discontinued between the three-month mark and one year
In a long-term study lasting nearly two years, people using Wegovy with lifestyle changes lost an average of about 15% of their body weight
However, for inflammatory factors, since there were no changes in gene expression due to the drug treatment, protein levels were not measured
