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If you have not explored this, the dietary changes that GLP-1 medications necessitate might be a good time to trial a gluten-free period and assess symptom response

High-fat and greasy meals can amplify GI side effects, which may already be heightened after an accidental muscle injection

Semaglutide tends to be the better fit when: the goal is a 10 to 15 percent weight reduction, the patient has documented cardiovascular disease or is at high cardiovascular risk and wants the medication with the most outcomes data, cost or access constraints favor it, or the patient has tolerated single-pathway GLP-1s well in the past

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This significantly increases the risk of adverse effects including nausea, vomiting, and hypoglycaemia