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have anti-inflammatory, anti-ischemic and anti-fibrotic effects and inhibit myocardiocyte apoptosis.29,32,42 More recently, it has been reported that they also reduce epicardial fat.43 They also inhibit platelet aggregation and thrombosis.44 In the lungs, rGLP-1 activation conferred protection against lipopolysaccharide-induced acute lung injury.45 In adipose tissue they favor adipocyte differentiation, decreases lipid deposition in white fat and facilitate its conversion to brown fat, as well as thermogenesis and energy consumption29,32,4648

Many patients also report less persistent food noise, fewer intense cravings, and greater ability to follow through on nutrition changes

KPV targets inflammation via NF-kB inhibition with preferential uptake in inflamed gut tissue

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a GP or registered dietitian can provide personalised guidance based on clinical context