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This is higher than other GLP-1s, which had discontinuation rates of 6.1% (tirzepatide), 8.0% (semaglutide) and 10.3% (orforglipron)
Even when lab values appear normal on medication, many patients still struggle with: Slowed metabolism Insulin resistance Increased fat storage Chronic inflammation Fatigue that limits physical activity These factors create a perfect storm where calorie restriction backfires, muscle mass declines, and weight loss stalls
The human body doesnt naturally produce vitamin B12, so if you dont have it in your diet, you might be at risk of deficiency
Anderson-Hunt, A
After that, the preservative effect diminishes and contamination risk increases even with proper technique
