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Dehydration worsens headaches, constipation, and fatigue, all of which are common complaints during weight loss protocols

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In addition, oral supplementation with acetyl-l-carnitine at a daily dose of 3000 mg is listed in the table of neuropathic pain treatment amongst tier 1 agents included in the Mayo Clinic guidelines on peripheral neuropathies [10]

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This approach may also help to overcome resistance mechanisms based on the modification of LPS through the addition of l-Ara4N [97]