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Nervous system: IGF-1 has neuroprotective properties and supports cognitive function
Cagrilintide trials have shown weight loss results of roughly 2023% in certain combination study arms, making it one of the most closely studied amylin receptor agonists in current clinical investigation
Li H, Toh PZ, Tan JY, Zin MT, Lee CY, Li B, Leolukman M, Bao H, Kang L
2014;134:1175e11861177
A 2015 review in the Journal of Clinical Endocrinology confirming that GHRH analogs combined with ghrelin-pathway agonists produce a synergistic GH secretory response that exceeds additive effects when either compound is used alone provides the mechanistic basis for why combination therapy is the standard in supervised clinical settings
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