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High-dose supplementation, particularly hydroxocobalamin injections, has been associated with acne-like eruptions and rosacea flare-ups in susceptible individuals
The criteria for referral are a BMI over 35 and at least one weight-related health condition like PMOS (formerly PCOS), type 2 diabetes or high blood pressure
In the SUSTAIN-6 trial, semaglutide demonstrated cardiovascular benefits in adults with type 2 diabetes at high cardiovascular risk, though it is important to note this is not a UK-licensed cardiovascular indication
Most gastrointestinal side effects from Wegovy are most pronounced during the first 48 weeks of treatment and during dose escalation
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