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Tranquility provides a way to destroy enchantments, but not artifacts, so it is at best a sideboard card

Doctor's companion (You can have two commanders if the other is the Doctor.) If you choose no target for Ace's Nitro-9 ability, you will put a +1/+1 counter on it

Lilianas Talent also destroys any creature which damages the enchanted Planeswalker

If you were playing the typical all Detention Sphere suite of removal, you would need to either play the counterspell right away or tap out on your next turn to answer it and thus render yourself unable to defend with permission on your opponents next turn if they cast a really spicy card

Mickey Mouse, Pirate Captain turns something simple, such as a Moana, Self-Taught Sailor, into a banish-anything-for-free powerhouse