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The same is true for any counters that change its power and/or toughness and effects that switch its power and toughness

You choosing, even from a restricted selection of cards has a lot more disruptive capabilities and random can do worse still

Make sure to use Gemhide Sliver and Manaweft Sliver as well

In this situation, The Queen will lower the enemys willpower equal to her strength value and her willpower will be lower by the opposing characters strength value

There are a multitude of different artifact decks that can make excellent use of its abilities, particularly that third one, and it may well allow for some truly nauseating combos